Genome Evolution Course - 2009

Evolution by Gene Duplication

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Presentation: PPT or PDF

Essay version

Topics

• Preponderance of paralogs (gene duplicates) in genomes
• The fate of duplicate genes
• The consequences of gene duplication for speciation
• Preservation of duplicates by subfunctionalization
• An example of adaptive evolution
• Constructive neutral evolution

Suggested readings

• The fate and consequences of duplicate genes
• Preservation of duplicate genes by complementary, degenrative mutations
• Adaptive evolution of a duplicated pancreatic ribonuclease gene in a leaf-eating monkey

Assignment

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Back to the Genome Evolution Course.

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Itai Yanai, yanai@technion.ac.il